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[guojia] => the European Society of Anaesthesiology and Intens
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[tjyjyw] =>
[lyyw] => We recommend that a multidisciplinary team meeting should decide on the peri-operative use of APAs in urgent and semi-urgent surgery. （Evidence level: low；Recommendation grade: strong）
[laiyuan] => 建议在紧急和半紧急手术中，通过多学科团队会议决定围手术期抗血小板药物的使用。（证据级别：低；推荐强度：强推荐）
[znzldj] => B
[_inputtime] => 1704957867
[_updatetime] => 1704957867
[_nrjc] =>
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)
推荐意见
建议在紧急和半紧急手术中，通过多学科团队会议决定围手术期抗血小板药物的使用。（证据级别：低；推荐强度：强推荐）
We recommend that a multidisciplinary team meeting should decide on the peri-operative use of APAs in urgent and semi-urgent surgery. （Evidence level: low；Recommendation grade: strong）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
Array
(
[id] => 1246
[catid] => 297
[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
[thumb] =>
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[tjqd] =>
[nianfen] => 2023
[guojia] => the European Society of Anaesthesiology and Intens
[pdf] =>
[tjyjyw] =>
[lyyw] => Noncardiac elective surgery should be postponed until completion of the full course of DAPT. （Evidence level: high；Recommendation grade: strong）
[laiyuan] => 非心脏择期手术应推迟至完成全疗程的双重抗血小板治疗。（证据级别：高；推荐强度：强推荐）
[znzldj] => B
[_inputtime] => 1704957867
[_updatetime] => 1704957867
[_nrjc] =>
[_nrsh] =>
)
推荐意见
非心脏择期手术应推迟至完成全疗程的双重抗血小板治疗。（证据级别：高；推荐强度：强推荐）
Noncardiac elective surgery should be postponed until completion of the full course of DAPT. （Evidence level: high；Recommendation grade: strong）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
Array
(
[id] => 1247
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[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
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[tjqd] =>
[nianfen] => 2023
[guojia] => the European Society of Anaesthesiology and Intens
[pdf] =>
[tjyjyw] =>
[lyyw] => We suggest that urgent or semi-urgent surgery should be performed under aspirin/clopidogrel or aspirin/prasugrel combination therapy, if possible, or at least under aspirin alone. （Evidence level: low；Recommendation grade: weak）
[laiyuan] => 建议紧急或半紧急手术尽可能在阿司匹林/氯吡格雷或阿司匹林/普拉格雷联合治疗的情况下进行，或至少在阿司匹林单独治疗的情况下进行。（证据级别：低；推荐强度：弱推荐）
[znzldj] => B
[_inputtime] => 1704957867
[_updatetime] => 1704957867
[_nrjc] =>
[_nrsh] =>
)
推荐意见
建议紧急或半紧急手术尽可能在阿司匹林/氯吡格雷或阿司匹林/普拉格雷联合治疗的情况下进行，或至少在阿司匹林单独治疗的情况下进行。（证据级别：低；推荐强度：弱推荐）
We suggest that urgent or semi-urgent surgery should be performed under aspirin/clopidogrel or aspirin/prasugrel combination therapy, if possible, or at least under aspirin alone. （Evidence level: low；Recommendation grade: weak）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
Array
(
[id] => 1248
[catid] => 297
[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
[thumb] =>
[keywords] =>
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[author] => 系统管理员
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[zjfj] =>
[tjqd] =>
[nianfen] => 2023
[guojia] => the European Society of Anaesthesiology and Intens
[pdf] =>
[tjyjyw] =>
[lyyw] => We suggest that platelet transfusion be considered in cases of intra-operative or postoperative bleeding supposedly related to clopidogrel or prasugrel. A higher dose than that used to neutralise aspirin is proposed for P2Y12 inhibitors. （Evidence level: low；Recommendation grade: weak）
[laiyuan] => 建议在术中或术后存在可能与氯吡格雷或普拉格雷有关的出血的情况下考虑血小板输注。对于P2Y12抑制剂的使用剂量，建议采用高于阿司匹林中和剂量。（证据级别：低；推荐强度：弱推荐）
[znzldj] => B
[_inputtime] => 1704957867
[_updatetime] => 1704957867
[_nrjc] =>
[_nrsh] =>
)
推荐意见
建议在术中或术后存在可能与氯吡格雷或普拉格雷有关的出血的情况下考虑血小板输注。对于P2Y12抑制剂的使用剂量，建议采用高于阿司匹林中和剂量。（证据级别：低；推荐强度：弱推荐）
We suggest that platelet transfusion be considered in cases of intra-operative or postoperative bleeding supposedly related to clopidogrel or prasugrel. A higher dose than that used to neutralise aspirin is proposed for P2Y12 inhibitors. （Evidence level: low；Recommendation grade: weak）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
Array
(
[id] => 1249
[catid] => 297
[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
[thumb] =>
[keywords] =>
[description] =>
[hits] =>
[uid] => 1
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[url] => https://www.anes-guide.com/show/1249.html
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[xzl] => 0
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[demo_url] =>
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[zjfj] =>
[tjqd] =>
[nianfen] => 2023
[guojia] => the European Society of Anaesthesiology and Intens
[pdf] =>
[tjyjyw] =>
[lyyw] => In high thrombotic risk patients under DAPT, if the interruption of P2Y12 receptor inhibitors is considered unacceptable by a multidisciplinary team, bridging with the ultra-short acting P2Y12 receptor inhibitor (cangrelor) or short-acting glycoprotein IIbIIIa inhibitors may be considered. （Evidence level: low；Recommendation grade: weak）
[laiyuan] => 在接受双联抗血小板治疗的高血栓风险患者中，如果多学科团队认为无法中断P2Y12受体抑制剂治疗，则可考虑使用超短效P2Y12受体抑制剂(坎格雷洛)或短效糖蛋白IIb IIIa抑制剂进行过渡治疗。（证据级别：低；推荐强度：弱推荐）
[znzldj] => B
[_inputtime] => 1704957867
[_updatetime] => 1704957867
[_nrjc] =>
[_nrsh] =>
)
推荐意见
在接受双联抗血小板治疗的高血栓风险患者中，如果多学科团队认为无法中断P2Y12受体抑制剂治疗，则可考虑使用超短效P2Y12受体抑制剂(坎格雷洛)或短效糖蛋白IIb IIIa抑制剂进行过渡治疗。（证据级别：低；推荐强度：弱推荐）
In high thrombotic risk patients under DAPT, if the interruption of P2Y12 receptor inhibitors is considered unacceptable by a multidisciplinary team, bridging with the ultra-short acting P2Y12 receptor inhibitor (cangrelor) or short-acting glycoprotein IIbIIIa inhibitors may be considered. （Evidence level: low；Recommendation grade: weak）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
Array
(
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[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
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[guojia] => the European Society of Anaesthesiology and Intens
[pdf] =>
[tjyjyw] =>
[lyyw] => We recommend that severe bleeding associated with i.v.unfractionated heparin (UFH) should be treated with i.v.protamine at a dose of 1 mg per 100 IU UFH given in the preceding 2 to 3 h. （Evidence level: high；Recommendation grade: strong）
[laiyuan] => 对于静脉注射普通肝素（UFH）相关的严重出血，应静脉注射鱼精蛋白治疗（前2 ~ 3小时内每100 IU UFH用药 1mg）。（证据级别：高；推荐强度：强推荐）
[znzldj] => B
[_inputtime] => 1704957867
[_updatetime] => 1704957867
[_nrjc] =>
[_nrsh] =>
)
推荐意见
对于静脉注射普通肝素（UFH）相关的严重出血，应静脉注射鱼精蛋白治疗（前2 ~ 3小时内每100 IU UFH用药 1mg）。（证据级别：高；推荐强度：强推荐）
We recommend that severe bleeding associated with i.v.unfractionated heparin (UFH) should be treated with i.v.protamine at a dose of 1 mg per 100 IU UFH given in the preceding 2 to 3 h. （Evidence level: high；Recommendation grade: strong）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
Array
(
[id] => 1251
[catid] => 297
[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
[thumb] =>
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[zjfj] =>
[tjqd] =>
[nianfen] => 2023
[guojia] => the European Society of Anaesthesiology and Intens
[pdf] =>
[tjyjyw] =>
[lyyw] => We suggest that severe bleeding associated with subcutaneous UFH unresponsive to i.v. protamine at a dose of 1 mg per 100 IU UFH could be treated by continuous administration of i.v. protamine, with the dose guided by anti-Xa activity and if not available by activated partial thromboplastin time (aPTT).（Evidence level: low；Recommendation grade: weak）
[laiyuan] => 我们建议，每100IU依诺肝素静脉注射1mg鱼精蛋白，可通过持续静脉注射鱼精蛋白治疗与皮下依诺肝素相关的严重出血，剂量以抗xa活性为指导，如果不能通过激活部分凝血活素时间(aPTT)。（证据级别：低；推荐强度：弱推荐）
[znzldj] => B
[_inputtime] => 1704957867
[_updatetime] => 1704957867
[_nrjc] =>
[_nrsh] =>
)
推荐意见
我们建议，每100IU依诺肝素静脉注射1mg鱼精蛋白，可通过持续静脉注射鱼精蛋白治疗与皮下依诺肝素相关的严重出血，剂量以抗xa活性为指导，如果不能通过激活部分凝血活素时间(aPTT)。（证据级别：低；推荐强度：弱推荐）
We suggest that severe bleeding associated with subcutaneous UFH unresponsive to i.v. protamine at a dose of 1 mg per 100 IU UFH could be treated by continuous administration of i.v. protamine, with the dose guided by anti-Xa activity and if not available by activated partial thromboplastin time (aPTT).（Evidence level: low；Recommendation grade: weak）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
Array
(
[id] => 1252
[catid] => 297
[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
[thumb] =>
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[tjqd] =>
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[guojia] => the European Society of Anaesthesiology and Intens
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[tjyjyw] =>
[lyyw] => We suggest that severe bleeding related to subcutaneous low-molecular-weight heparin (LMWH) should be treated with i.v. protamine at a dose of 1 mg per 100 anti-FXa units of LMWH administered and, if unresponsive, antiXa activity should be measured.（Evidence level: low；Recommendation grade: weak）
[laiyuan] => 我们建议，与皮下低分子量肝素(LMWH)相关的严重出血应静脉注射鱼精蛋白治疗，剂量为每100个低分子量肝素抗FXa单位1mg，如果无反应，应测量抗Xa活性。（证据级别：低；推荐强度：弱推荐）
[znzldj] => B
[_inputtime] => 1704957867
[_updatetime] => 1704957867
[_nrjc] =>
[_nrsh] =>
)
推荐意见
我们建议，与皮下低分子量肝素(LMWH)相关的严重出血应静脉注射鱼精蛋白治疗，剂量为每100个低分子量肝素抗FXa单位1mg，如果无反应，应测量抗Xa活性。（证据级别：低；推荐强度：弱推荐）
We suggest that severe bleeding related to subcutaneous low-molecular-weight heparin (LMWH) should be treated with i.v. protamine at a dose of 1 mg per 100 anti-FXa units of LMWH administered and, if unresponsive, antiXa activity should be measured.（Evidence level: low；Recommendation grade: weak）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
Array
(
[id] => 1253
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[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
[thumb] =>
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[guojia] => the European Society of Anaesthesiology and Intens
[pdf] =>
[tjyjyw] =>
[lyyw] => We suggest that the administration of rFVIIa could be considered to treat severe bleeding associated with subcutaneous administration of fondaparinux.（Evidence level: low；Recommendation grade: weak）
[laiyuan] => 重组活化因子VII（rFVIIa）可考虑用于治疗磺达肝癸钠皮下给药相关的严重出血(超说明书用药)。（证据级别：低；推荐强度：弱推荐）
[znzldj] => B
[_inputtime] => 1704957867
[_updatetime] => 1704957867
[_nrjc] =>
[_nrsh] =>
)
推荐意见
重组活化因子VII（rFVIIa）可考虑用于治疗磺达肝癸钠皮下给药相关的严重出血(超说明书用药)。（证据级别：低；推荐强度：弱推荐）
We suggest that the administration of rFVIIa could be considered to treat severe bleeding associated with subcutaneous administration of fondaparinux.（Evidence level: low；Recommendation grade: weak）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
Array
(
[id] => 1254
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[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
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[guojia] => the European Society of Anaesthesiology and Intens
[pdf] =>
[tjyjyw] =>
[lyyw] => We recommend that vitamin K antagonists (VKAs) should not be interrupted in patients undergoing lowbleeding-risk procedures: skin surgery, dental and stomatological procedures, gastric and colonic endoscopies (even if biopsy is scheduled but not polypectomies), nor for most ophthalmological surgery, mainly anterior chamber (cataract).（Evidence level: low；Recommendation grade: strong）
[laiyuan] => 对于接受低出血风险手术(如皮肤手术、牙科和口腔手术、胃和结肠内镜检查(即使计划进行活检，但不包括息肉切除术)以及大多数眼科手术（主要是前房、白内障手术）的患者，不应中断VKAs治疗。（证据级别：低；推荐强度：强推荐）
[znzldj] => B
[_inputtime] => 1704957867
[_updatetime] => 1704957867
[_nrjc] =>
[_nrsh] =>
)
推荐意见
对于接受低出血风险手术(如皮肤手术、牙科和口腔手术、胃和结肠内镜检查(即使计划进行活检，但不包括息肉切除术)以及大多数眼科手术（主要是前房、白内障手术）的患者，不应中断VKAs治疗。（证据级别：低；推荐强度：强推荐）
We recommend that vitamin K antagonists (VKAs) should not be interrupted in patients undergoing lowbleeding-risk procedures: skin surgery, dental and stomatological procedures, gastric and colonic endoscopies (even if biopsy is scheduled but not polypectomies), nor for most ophthalmological surgery, mainly anterior chamber (cataract).（Evidence level: low；Recommendation grade: strong）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
