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[lyyw] => We recommend prophylactic administration of TXA [or if not available e-aminocaproic acid (EACA)] before cardiopulmonary bypass (CPB) to reduce postoperative blood loss and blood transfusion requirements.（Evidence level: moderate；Recommendation grade: strong）
[laiyuan] => 我们建议在体外循环(心肺旁路)前预防性应用氨甲环酸（或者 e-氨基己酸），以减少术后失血和输血需求。（证据级别：中；推荐强度：强推荐）
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)
推荐意见
我们建议在体外循环(心肺旁路)前预防性应用氨甲环酸（或者 e-氨基己酸），以减少术后失血和输血需求。（证据级别：中；推荐强度：强推荐）
We recommend prophylactic administration of TXA [or if not available e-aminocaproic acid (EACA)] before cardiopulmonary bypass (CPB) to reduce postoperative blood loss and blood transfusion requirements.（Evidence level: moderate；Recommendation grade: strong）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
Array
(
[id] => 1303
[catid] => 297
[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
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[tjyjyw] =>
[lyyw] => If systemic administration of TXA is contraindicated (for refractory seizure), topical TXA is suggested.（Evidence level: low；Recommendation grade: weak）
[laiyuan] => 如果氨甲环酸全身给药受限制(用于难治性癫痫发作)，建议局部使用氨甲环酸。（证据级别：低；推荐强度：弱推荐）
[znzldj] => B
[_inputtime] => 1704957869
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)
推荐意见
如果氨甲环酸全身给药受限制(用于难治性癫痫发作)，建议局部使用氨甲环酸。（证据级别：低；推荐强度：弱推荐）
If systemic administration of TXA is contraindicated (for refractory seizure), topical TXA is suggested.（Evidence level: low；Recommendation grade: weak）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
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[id] => 1304
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[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
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[tjyjyw] =>
[lyyw] => Upon withdrawal from CPB, we suggest the use of heparin monitoring to avoid protamine-to-heparin dosing ratios above 1.（Evidence level: moderate；Recommendation grade: weak）
[laiyuan] => CBP停机时，我们建议使用肝素监测以避免鱼精蛋白与肝素的剂量比超过1。（证据级别：中；推荐强度：弱推荐）
[znzldj] => B
[_inputtime] => 1704957869
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推荐意见
CBP停机时，我们建议使用肝素监测以避免鱼精蛋白与肝素的剂量比超过1。（证据级别：中；推荐强度：弱推荐）
Upon withdrawal from CPB, we suggest the use of heparin monitoring to avoid protamine-to-heparin dosing ratios above 1.（Evidence level: moderate；Recommendation grade: weak）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
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(
[id] => 1305
[catid] => 297
[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
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[guojia] => the European Society of Anaesthesiology and Intens
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[tjyjyw] =>
[lyyw] => We recommend treatment with fibrinogen concentrate or cryoprecipitate, if bleeding is accompanied by hypo-fibrinogenaemia (viscoelastic signs of a functional fibrinogen deficit or a plasma Clauss fibrinogen level ≤1.5 g l 1).（Evidence level: moderate；Recommendation grade: strong）
[laiyuan] => 如果出血伴有低纤维蛋白原血症(功能性纤维蛋白原缺乏的黏弹性体征或血浆纤维蛋白原水平≤1.5g/l)，我们建议使用纤维蛋白原浓缩物或冷沉淀治疗。（证据级别：中；推荐强度：强推荐）
[znzldj] => B
[_inputtime] => 1704957869
[_updatetime] => 1704957869
[_nrjc] =>
[_nrsh] =>
)
推荐意见
如果出血伴有低纤维蛋白原血症(功能性纤维蛋白原缺乏的黏弹性体征或血浆纤维蛋白原水平≤1.5g/l)，我们建议使用纤维蛋白原浓缩物或冷沉淀治疗。（证据级别：中；推荐强度：强推荐）
We recommend treatment with fibrinogen concentrate or cryoprecipitate, if bleeding is accompanied by hypo-fibrinogenaemia (viscoelastic signs of a functional fibrinogen deficit or a plasma Clauss fibrinogen level ≤1.5 g l 1).（Evidence level: moderate；Recommendation grade: strong）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
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[id] => 1306
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[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
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[tjqd] =>
[nianfen] => 2023
[guojia] => the European Society of Anaesthesiology and Intens
[pdf] =>
[tjyjyw] =>
[lyyw] => We recommend treatment with PCC if available instead of FFP if bleeding is accompanied by signs of coagulation factor deficiency (viscoelastic signs of a functional coagulation factor deficiency or a high PT ratio).（Evidence level: moderate；Recommendation grade: strong）
[laiyuan] => 如果出血伴有凝血因子缺乏的迹象(功能性凝血因子缺乏或凝血酶时间比率高的粘弹性迹象)，我们建议用凝血酶原复合物浓缩物(如果可用)代替新鲜冷冻血浆进行治疗。（证据级别：中；推荐强度：强推荐）
[znzldj] => B
[_inputtime] => 1704957869
[_updatetime] => 1704957869
[_nrjc] =>
[_nrsh] =>
)
推荐意见
如果出血伴有凝血因子缺乏的迹象(功能性凝血因子缺乏或凝血酶时间比率高的粘弹性迹象)，我们建议用凝血酶原复合物浓缩物(如果可用)代替新鲜冷冻血浆进行治疗。（证据级别：中；推荐强度：强推荐）
We recommend treatment with PCC if available instead of FFP if bleeding is accompanied by signs of coagulation factor deficiency (viscoelastic signs of a functional coagulation factor deficiency or a high PT ratio).（Evidence level: moderate；Recommendation grade: strong）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
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[lyyw] => We suggest that rFVIIa may be considered for patients with bleeding that remains intractable after conventional haemostatic therapy has been applied, although the risk of thrombosis must be taken into account.（Evidence level: moderate；Recommendation grade: weak）
[laiyuan] => 我们建议重组活化因子VII可用于常规止血治疗后仍难以控制的出血患者，尽管必须考虑血栓形成的风险。（证据级别：中；推荐强度：弱推荐）
[znzldj] => B
[_inputtime] => 1704957869
[_updatetime] => 1704957869
[_nrjc] =>
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)
推荐意见
我们建议重组活化因子VII可用于常规止血治疗后仍难以控制的出血患者，尽管必须考虑血栓形成的风险。（证据级别：中；推荐强度：弱推荐）
We suggest that rFVIIa may be considered for patients with bleeding that remains intractable after conventional haemostatic therapy has been applied, although the risk of thrombosis must be taken into account.（Evidence level: moderate；Recommendation grade: weak）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
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[tjyjyw] =>
[lyyw] => We recommend the use of standardised haemostatic algorithms with predefined intervention triggers over clinicians’discretion for the management of coagulopathy in cardiac surgery.（Evidence level: moderate；Recommendation grade: strong）
[laiyuan] => 我们建议使用标准化的止血算法和预先定义的干预触发，而不是临床医生的自由裁量权，以管理心脏手术中的凝血病。（证据级别：中；推荐强度：强推荐）
[znzldj] => B
[_inputtime] => 1704957869
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[_nrjc] =>
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)
推荐意见
我们建议使用标准化的止血算法和预先定义的干预触发，而不是临床医生的自由裁量权，以管理心脏手术中的凝血病。（证据级别：中；推荐强度：强推荐）
We recommend the use of standardised haemostatic algorithms with predefined intervention triggers over clinicians’discretion for the management of coagulopathy in cardiac surgery.（Evidence level: moderate；Recommendation grade: strong）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
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[tjyjyw] =>
[lyyw] => We suggest the use of point-of-care haemostatic testing over conventional coagulation assays for the management of coagulopathy in cardiac surgery.（Evidence level: low；Recommendation grade: weak）
[laiyuan] => 我们建议在心脏手术中使用床旁止血检测代替常规凝血检测来管理凝血病。（证据级别：低；推荐强度：弱推荐）
[znzldj] => B
[_inputtime] => 1704957869
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推荐意见
我们建议在心脏手术中使用床旁止血检测代替常规凝血检测来管理凝血病。（证据级别：低；推荐强度：弱推荐）
We suggest the use of point-of-care haemostatic testing over conventional coagulation assays for the management of coagulopathy in cardiac surgery.（Evidence level: low；Recommendation grade: weak）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
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[tjyjyw] =>
[lyyw] => In patients on ticagrelor or rivaroxaban undergoing emergency cardiac/aortic surgery on CPB, haemo-adsorption may be considered as an adjuvant therapy to reduce bleeding complications.（Evidence level: low；Recommendation grade: weak）
[laiyuan] => 在使用替卡格雷或利伐沙班的患者在体外循环下进行紧急心脏/主动脉手术时，血液吸附可以被认为是一种辅助治疗，以减少出血并发症。（证据级别：低；推荐强度：弱推荐）
[znzldj] => B
[_inputtime] => 1704957869
[_updatetime] => 1704957869
[_nrjc] =>
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)
推荐意见
在使用替卡格雷或利伐沙班的患者在体外循环下进行紧急心脏/主动脉手术时，血液吸附可以被认为是一种辅助治疗，以减少出血并发症。（证据级别：低；推荐强度：弱推荐）
In patients on ticagrelor or rivaroxaban undergoing emergency cardiac/aortic surgery on CPB, haemo-adsorption may be considered as an adjuvant therapy to reduce bleeding complications.（Evidence level: low；Recommendation grade: weak）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
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[guojia] => the European Society of Anaesthesiology and Intens
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[tjyjyw] =>
[lyyw] => We suggest the use of acute normovolaemic haemodilution (ANH) in cardiac surgical patients with normal/high initial Hb concentration.（Evidence level: low；Recommendation grade: weak）
[laiyuan] => 我们建议对初始血红蛋白浓度正常/高的心脏外科患者使用急性等容性血液稀释(ANH)。（证据级别：低；推荐强度：弱推荐）
[znzldj] => B
[_inputtime] => 1704957869
[_updatetime] => 1704957869
[_nrjc] =>
[_nrsh] =>
)
推荐意见
我们建议对初始血红蛋白浓度正常/高的心脏外科患者使用急性等容性血液稀释(ANH)。（证据级别：低；推荐强度：弱推荐）
We suggest the use of acute normovolaemic haemodilution (ANH) in cardiac surgical patients with normal/high initial Hb concentration.（Evidence level: low；Recommendation grade: weak）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
