Dynamic platelet count decrease or a level less than150×10^9 /l at the onset of labour, particularly if combined with plasma fibrinogen level less than 2.0 g/l, may indicate an increased risk of postpartum haemorrhage.（Evidence level: low）

At the beginning of labour, aPTT and PT are of little predictive value for postpartum haemorrhage. （Evidence level: low）

VHA can identify obstetric coagulopathy including hypo-fibrinogenaemia and reduced platelet level. （Evidence level: moderate）

We suggest, in cases of ongoing bleeding as part of a goaldirected coagulation therapy algorithm ，monitoring FXIII and correction of deficiency. （Evidence level: low；Recommendation grade: weak）

We suggest the intra-operative and postoperative use of cell salvage in major orthopaedic procedures with high risk of bleeding. （Evidence level: moderate；Recommendation grade: weak）

We recommend a low central venous pressure (CVP) and restrictive fluid administration during liver surgery to reduce bleeding. （Evidence level:high；Recommendation grade: strong）

Intra-operative hypovolaemic phlebotomy or infrahepatic inferior vena cava clamping used together with low CVP strategy are suggested for decreasing intra-operative blood loss and transfusion requirements in selected patients undergoing major liver resections.（Evidence level: low；Recommendation grade:weak）

Maintenance of high-stroke volume variation (10 to 20%) could be considered in liver resection surgery to reduce bleeding. （Evidence level: moderate；Recommendation grade: weak）

During the liver resection phase, ventilation with low airway pressures achieved by low tidal volumes, and without positive end-expiratory pressure is suggested along with a low CVP strategy to decrease intra operative bleeding.（Evidence level: moderate；Recommendation grade: weak）

Together with other measures, terlipressin infusion may be considered during hepato-pancreatico-biliary (HPB) surgery to reduce bleeding.（Evidence level: moderate；Recommendation grade: weak）