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[guojia] => the European Society of Anaesthesiology and Intens
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[tjyjyw] =>
[lyyw] => We recommend that antiplatelet agent (APA) therapy should resume as soon as possible postoperatively to prevent platelet activation and ischaemic events. （Evidence level: low；Recommendation grade: strong）
[laiyuan] => 我们建议术后应尽快恢复抗血小板药物（APA）治疗，以防止血小板活化和缺血性事件的发生。（证据级别：低；推荐强度：强推荐）
[znzldj] => B
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推荐意见
我们建议术后应尽快恢复抗血小板药物（APA）治疗，以防止血小板活化和缺血性事件的发生。（证据级别：低；推荐强度：强推荐）
We recommend that antiplatelet agent (APA) therapy should resume as soon as possible postoperatively to prevent platelet activation and ischaemic events. （Evidence level: low；Recommendation grade: strong）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
Array
(
[id] => 1243
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[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
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[tjyjyw] =>
[lyyw] => If P2Y12 inhibitors have to be discontinued peri-operatively, they should be resumed early, if possible within 24 to 72 h after surgery, given the increased thrombotic risk. Resumption should be with the same P2Y12 inhibitor as pre-operatively. No recommendation can be made regarding the use or not of a loading dose.（Evidence level: low；Recommendation grade: weak）
[laiyuan] => 如果围手术期必须停用P2Y12抑制剂，则应尽早恢复，如果可能，应在术后24-72小时内恢复，因为血栓形成风险增加。恢复时应使用与术前相同的P2Y12抑制剂。不能就是否使用负荷剂量提出建议。（证据级别：低；推荐强度：弱推荐）
[znzldj] => B
[_inputtime] => 1704957867
[_updatetime] => 1704957867
[_nrjc] =>
[_nrsh] =>
)
推荐意见
如果围手术期必须停用P2Y12抑制剂，则应尽早恢复，如果可能，应在术后24-72小时内恢复，因为血栓形成风险增加。恢复时应使用与术前相同的P2Y12抑制剂。不能就是否使用负荷剂量提出建议。（证据级别：低；推荐强度：弱推荐）
If P2Y12 inhibitors have to be discontinued peri-operatively, they should be resumed early, if possible within 24 to 72 h after surgery, given the increased thrombotic risk. Resumption should be with the same P2Y12 inhibitor as pre-operatively. No recommendation can be made regarding the use or not of a loading dose.（Evidence level: low；Recommendation grade: weak）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
Array
(
[id] => 1244
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[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
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[tjyjyw] =>
[lyyw] => We recommend against peri-operative use of nonsteroidal anti-inflammatory drugs in patients treated with dual antiplatelet therapy (DAPT); peri-operative use of coxibs is possible.（Evidence level: low；Recommendation grade: strong）
[laiyuan] => 我们不建议接受双重抗血小板治疗(DAPT)的患者围手术期使用非甾体类抗炎药;围手术期可以使用昔布类。（证据级别：低；推荐强度：强推荐）
[znzldj] => B
[_inputtime] => 1704957867
[_updatetime] => 1704957867
[_nrjc] =>
[_nrsh] =>
)
推荐意见
我们不建议接受双重抗血小板治疗(DAPT)的患者围手术期使用非甾体类抗炎药;围手术期可以使用昔布类。（证据级别：低；推荐强度：强推荐）
We recommend against peri-operative use of nonsteroidal anti-inflammatory drugs in patients treated with dual antiplatelet therapy (DAPT); peri-operative use of coxibs is possible.（Evidence level: low；Recommendation grade: strong）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
Array
(
[id] => 1245
[catid] => 297
[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
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[tjyjyw] =>
[lyyw] => We recommend that a multidisciplinary team meeting should decide on the peri-operative use of APAs in urgent and semi-urgent surgery. （Evidence level: low；Recommendation grade: strong）
[laiyuan] => 建议在紧急和半紧急手术中，通过多学科团队会议决定围手术期抗血小板药物的使用。（证据级别：低；推荐强度：强推荐）
[znzldj] => B
[_inputtime] => 1704957867
[_updatetime] => 1704957867
[_nrjc] =>
[_nrsh] =>
)
推荐意见
建议在紧急和半紧急手术中，通过多学科团队会议决定围手术期抗血小板药物的使用。（证据级别：低；推荐强度：强推荐）
We recommend that a multidisciplinary team meeting should decide on the peri-operative use of APAs in urgent and semi-urgent surgery. （Evidence level: low；Recommendation grade: strong）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
Array
(
[id] => 1246
[catid] => 297
[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
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[tjqd] =>
[nianfen] => 2023
[guojia] => the European Society of Anaesthesiology and Intens
[pdf] =>
[tjyjyw] =>
[lyyw] => Noncardiac elective surgery should be postponed until completion of the full course of DAPT. （Evidence level: high；Recommendation grade: strong）
[laiyuan] => 非心脏择期手术应推迟至完成全疗程的双重抗血小板治疗。（证据级别：高；推荐强度：强推荐）
[znzldj] => B
[_inputtime] => 1704957867
[_updatetime] => 1704957867
[_nrjc] =>
[_nrsh] =>
)
推荐意见
非心脏择期手术应推迟至完成全疗程的双重抗血小板治疗。（证据级别：高；推荐强度：强推荐）
Noncardiac elective surgery should be postponed until completion of the full course of DAPT. （Evidence level: high；Recommendation grade: strong）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
Array
(
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[tjyjyw] =>
[lyyw] => We suggest that urgent or semi-urgent surgery should be performed under aspirin/clopidogrel or aspirin/prasugrel combination therapy, if possible, or at least under aspirin alone. （Evidence level: low；Recommendation grade: weak）
[laiyuan] => 建议紧急或半紧急手术尽可能在阿司匹林/氯吡格雷或阿司匹林/普拉格雷联合治疗的情况下进行，或至少在阿司匹林单独治疗的情况下进行。（证据级别：低；推荐强度：弱推荐）
[znzldj] => B
[_inputtime] => 1704957867
[_updatetime] => 1704957867
[_nrjc] =>
[_nrsh] =>
)
推荐意见
建议紧急或半紧急手术尽可能在阿司匹林/氯吡格雷或阿司匹林/普拉格雷联合治疗的情况下进行，或至少在阿司匹林单独治疗的情况下进行。（证据级别：低；推荐强度：弱推荐）
We suggest that urgent or semi-urgent surgery should be performed under aspirin/clopidogrel or aspirin/prasugrel combination therapy, if possible, or at least under aspirin alone. （Evidence level: low；Recommendation grade: weak）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
Array
(
[id] => 1248
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[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
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[zjfj] =>
[tjqd] =>
[nianfen] => 2023
[guojia] => the European Society of Anaesthesiology and Intens
[pdf] =>
[tjyjyw] =>
[lyyw] => We suggest that platelet transfusion be considered in cases of intra-operative or postoperative bleeding supposedly related to clopidogrel or prasugrel. A higher dose than that used to neutralise aspirin is proposed for P2Y12 inhibitors. （Evidence level: low；Recommendation grade: weak）
[laiyuan] => 建议在术中或术后存在可能与氯吡格雷或普拉格雷有关的出血的情况下考虑血小板输注。对于P2Y12抑制剂的使用剂量，建议采用高于阿司匹林中和剂量。（证据级别：低；推荐强度：弱推荐）
[znzldj] => B
[_inputtime] => 1704957867
[_updatetime] => 1704957867
[_nrjc] =>
[_nrsh] =>
)
推荐意见
建议在术中或术后存在可能与氯吡格雷或普拉格雷有关的出血的情况下考虑血小板输注。对于P2Y12抑制剂的使用剂量，建议采用高于阿司匹林中和剂量。（证据级别：低；推荐强度：弱推荐）
We suggest that platelet transfusion be considered in cases of intra-operative or postoperative bleeding supposedly related to clopidogrel or prasugrel. A higher dose than that used to neutralise aspirin is proposed for P2Y12 inhibitors. （Evidence level: low；Recommendation grade: weak）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
Array
(
[id] => 1249
[catid] => 297
[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
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[zjfj] =>
[tjqd] =>
[nianfen] => 2023
[guojia] => the European Society of Anaesthesiology and Intens
[pdf] =>
[tjyjyw] =>
[lyyw] => In high thrombotic risk patients under DAPT, if the interruption of P2Y12 receptor inhibitors is considered unacceptable by a multidisciplinary team, bridging with the ultra-short acting P2Y12 receptor inhibitor (cangrelor) or short-acting glycoprotein IIbIIIa inhibitors may be considered. （Evidence level: low；Recommendation grade: weak）
[laiyuan] => 在接受双联抗血小板治疗的高血栓风险患者中，如果多学科团队认为无法中断P2Y12受体抑制剂治疗，则可考虑使用超短效P2Y12受体抑制剂(坎格雷洛)或短效糖蛋白IIb IIIa抑制剂进行过渡治疗。（证据级别：低；推荐强度：弱推荐）
[znzldj] => B
[_inputtime] => 1704957867
[_updatetime] => 1704957867
[_nrjc] =>
[_nrsh] =>
)
推荐意见
在接受双联抗血小板治疗的高血栓风险患者中，如果多学科团队认为无法中断P2Y12受体抑制剂治疗，则可考虑使用超短效P2Y12受体抑制剂(坎格雷洛)或短效糖蛋白IIb IIIa抑制剂进行过渡治疗。（证据级别：低；推荐强度：弱推荐）
In high thrombotic risk patients under DAPT, if the interruption of P2Y12 receptor inhibitors is considered unacceptable by a multidisciplinary team, bridging with the ultra-short acting P2Y12 receptor inhibitor (cangrelor) or short-acting glycoprotein IIbIIIa inhibitors may be considered. （Evidence level: low；Recommendation grade: weak）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
Array
(
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[tjyjyw] =>
[lyyw] => We recommend that severe bleeding associated with i.v.unfractionated heparin (UFH) should be treated with i.v.protamine at a dose of 1 mg per 100 IU UFH given in the preceding 2 to 3 h. （Evidence level: high；Recommendation grade: strong）
[laiyuan] => 对于静脉注射普通肝素（UFH）相关的严重出血，应静脉注射鱼精蛋白治疗（前2 ~ 3小时内每100 IU UFH用药 1mg）。（证据级别：高；推荐强度：强推荐）
[znzldj] => B
[_inputtime] => 1704957867
[_updatetime] => 1704957867
[_nrjc] =>
[_nrsh] =>
)
推荐意见
对于静脉注射普通肝素（UFH）相关的严重出血，应静脉注射鱼精蛋白治疗（前2 ~ 3小时内每100 IU UFH用药 1mg）。（证据级别：高；推荐强度：强推荐）
We recommend that severe bleeding associated with i.v.unfractionated heparin (UFH) should be treated with i.v.protamine at a dose of 1 mg per 100 IU UFH given in the preceding 2 to 3 h. （Evidence level: high；Recommendation grade: strong）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
Array
(
[id] => 1251
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[title] => Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care
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[tjyjyw] =>
[lyyw] => We suggest that severe bleeding associated with subcutaneous UFH unresponsive to i.v. protamine at a dose of 1 mg per 100 IU UFH could be treated by continuous administration of i.v. protamine, with the dose guided by anti-Xa activity and if not available by activated partial thromboplastin time (aPTT).（Evidence level: low；Recommendation grade: weak）
[laiyuan] => 我们建议，每100IU依诺肝素静脉注射1mg鱼精蛋白，可通过持续静脉注射鱼精蛋白治疗与皮下依诺肝素相关的严重出血，剂量以抗xa活性为指导，如果不能通过激活部分凝血活素时间(aPTT)。（证据级别：低；推荐强度：弱推荐）
[znzldj] => B
[_inputtime] => 1704957867
[_updatetime] => 1704957867
[_nrjc] =>
[_nrsh] =>
)
推荐意见
我们建议，每100IU依诺肝素静脉注射1mg鱼精蛋白，可通过持续静脉注射鱼精蛋白治疗与皮下依诺肝素相关的严重出血，剂量以抗xa活性为指导，如果不能通过激活部分凝血活素时间(aPTT)。（证据级别：低；推荐强度：弱推荐）
We suggest that severe bleeding associated with subcutaneous UFH unresponsive to i.v. protamine at a dose of 1 mg per 100 IU UFH could be treated by continuous administration of i.v. protamine, with the dose guided by anti-Xa activity and if not available by activated partial thromboplastin time (aPTT).（Evidence level: low；Recommendation grade: weak）
证据评价方法：GRADE
指南质量等级：B
年份：2023
国家：the European Society of Anaesthesiology and Intens
